In my opinion:

Meshtastic is MUCH easier to set up. Reticulum is very difficult to set up and requires a lot of time/work at the moment.

Reticulum has a lot of potential for more protocols, networking, apps, etc…
Meshtatic is very much made for messages and finding nodes.

Both work with LoRa.

Ive played around with both and was more successful with meshtastic (and meshcore). But Reticulum impressed me because I could send images over LoRa and could work with just about any networking. Which was interesting!

This is a good video showcasing RNode/Reticulum here: https://youtu.be/BsAMeMp1hlg?t=657